Test product spiked at reduced ranges with representative organisms (including the aerobic bacterium Staphylococcus aureus, spore forming bacterium Bacillus subtilis, anaerobic bacterium Clostridium sporogenes or the fungus Candida albicans) are used to be sure there is absolutely no inhibitory effect within the sample which may mask contaminants,

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Acid saccharin was evaluated for consequences on amphibian enhancement within an assay for teratogenicity in frog embryos as Portion of an interlaboratory validation examine. The mean median lethal focus, the concentration that induced malformations in 50% of the surviving embryos plus the teratogenic index ensuing from Individuals concentrations i

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